myamino · Research resources
How to read a peptide Certificate of Analysis
A practical checklist for matching a peptide COA to its batch and understanding reported methods, identity and purity results.
Start with the batch, not the headline percentage
A Certificate of Analysis (COA) records analytical information about a sample or batch. Before interpreting results, match the compound name and lot identifier to the material you are ordering. A report for a different lot cannot establish the results for your lot.
Check who tested it and what they tested
Look for the issuing laboratory, report identifier, sample identifier and analysis date. Check whether the report identifies the sample supplied to the laboratory and whether the testing covered that sample or a stated production batch. Ask the supplier to clarify missing identifiers and request the original report where available.
Read the method alongside the result
HPLC separates components under specified conditions. UV peak-area purity describes detected signals under that method; its interpretation depends on the separation and detection conditions. Check the method, detection wavelength, chromatogram and peak integration rather than comparing isolated percentages.
Check identity evidence separately
Mass spectrometry measures mass-to-charge information and can support identification of the intended peptide. Look for the expected mass, observed result and the laboratory’s interpretation. A matching intact mass alone does not establish every aspect of structure; the analytical approach must suit the identification question.
Ask about tests relevant to your experiment
A purity result does not automatically document peptide content, sterility, endotoxins or all possible contaminants. Confirm which tests were actually performed and whether they meet your laboratory’s requirements. Keep the report with your batch and purchasing records.
Finding myamino documents
Our COA library is being prepared. When documents are published, match the compound and batch identifiers before using them in your records. Contact our team about document availability for a particular lot before ordering.